Background:

This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

Applications:

ELISA, IHC

Name of antibody:

WEE1

Immunogen:

Synthetic peptide of human WEE1

Full name:

WEE1 G2 checkpoint kinase

Synonyms:

WEE1A; WEE1hu

SwissProt:

P30291

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human colorectal cancer; Human ovarian cancer

IHC Recommend dilution:

25-100