Background:

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.

Applications:

ELISA, IHC

Name of antibody:

MED16

Immunogen:

Fusion protein of human MED16

Full name:

mediator complex subunit 16

Synonyms：

DRIP92; THRAP5; TRAP95

SwissProt:

Q9Y2X0

ELISA Recommended dilution:

2000-5000

IHC positive control:

Human liver cancer and human thyroid cancer

IHC Recommend dilution:

25-100