Background:

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

Applications:

WB

Name of antibody:

NXF3

Immunogen:

Synthesized peptide derived from internal of human NXF3.

Full name:

nuclear RNA export factor 3

Synonyms：

0

SwissProt:

Q9H4D5

WB Predicted band size:

60 kDa

WB Positive control:

MCF-7 cells lysate

WB Recommended dilution:

500-3000